Antibody Details
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This antibody is stable when stored at 2-8°C. Do not freeze.
Specificity
Anti-Human HLA-DP recognizes a (Mr 26-34 kDa) class II major histocompatibility complex (MHC) antigen.1 The antibody recognizes a monomorphic determinant present on cells expressing DP1, DP2, DP3, DP4 and DP5.
Antigen Distribution
The HLA-DP antigen is present on approximately 10% of normal peripheral blood lymphocytes but not on resting peripheral T-lymphocytes. HLA-DP is present in low density on peripheral blood monocytes and mitogen-stimulated T-lymphoblasts. Anti-HLA-DP reacts with most B-cell lines.
Antigen Details
References & Citations
1. Lampson, L. A. et al. (1980) J. Immunol. 125:393
2. Yu, D. T. Y. et al. (1980) J. Exp. Med. 151:91
3. Warnke, R. et al. (1980) N. Eng. J. Med. 303:293
4. Wilkinson, KA et al. (2005) Infect Immun. 74(5):2991-8
