Unknown

This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.

This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Anti-Astrocytes (clone 10E4/R5) recognizes a (Mr 180-200 kD) protein.

The antigen recognized by this antibody is present on the cell surface of astrocytes.

Astrocytes (also known collectively as astroglia) are the most plentiful and diverse of the glial cells. They have a characteristic star-shape and are found in the brain. They perform many functions, including biochemical support of endothelial cells which form the blood-brain barrier, the provision of nutrients to the nervous tissue, and a principal role in the repair and scarring process in the brain. This antibody is suitable as an astrocyte marker and for studies associated with their functions, using immunochemical techniques.

1. Alberts, B. et al. (1989) Molecular Biology of the Cell, Garland Publishing, NY